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人才队伍

于 海



研究领域:动物病毒分子生物学与基因工程
电话/传真:021-34293773/021-54081818
电子邮件:haiyu@shvri.ac.cn
更多信息:比如实验室主页等

简历(200-500字):
博士,研究员。2008年毕业于中国农业科学院研究生院,获得博士学位。同年7月中国农业科学院滚球盘best365_bet365滚球_365滚球网址是多少工作。2012年8月至2013年12月在美国堪萨斯州立大学兽医学院进行学术访问。近年来主要从事猪病毒病分子流行病学、基因工程疫苗研制及分子致病机制等相关研究,先后主持或承担了国家国际科技合作子课题、国家自然科学基金、国家科技支撑计划、上海市科技攻关等项目。目前,本人在国内外专业期刊上正式发表论文96篇,其中SCI论文47篇,第一作者或通讯作者SCI论文17篇,授权专利5项。2010年10月获得了教育部和国务院学位委员会颁发的“全国百篇优秀博士论文奖”,2015年度入选“上海市闵行区领军人才”,2016年度入选中国农业科学院青年英才计划所级"科研英才培育工程"。

主持科研项目情况
(1)中央级公益性科研院所基本科研业务费项目“新型三源重组H1N1亚型猪流感病毒的分子致病机制研究”(2019JB05),2019-2021,主持;
(2)上海自然科学基金项目“新型核糖体移码蛋白PA-X在猪流感病毒感染过程中的作用及其分子机制研究”(16ZR1444000),2016-2019,主持;
(3)国家青年自然科学基金项目“禽源H1N1亚型流感病毒NA和M基因对重组猪流感病毒生物学特性的影响”(31201916),2013-2015,主持;
(4)国家国际合作项子课题项目“重大动物源性人兽共患病预防与控制的关键技术”(2010DFB33920),2011-2013,主持;
(5)中央级公益性科研院所基本科研业务费项目“重组猪流感灭活疫苗的研制”(2010JB02),2010-2012,主持。

代表论着
(1)Bao-Yang Ruan?, Feng Wen?, Xiao-Qian Gong, Xiao-Min Liu, Qi Wang, Ling-Xue Yu, Shuai-Yong Wang, Peng Zhang, Hai-Ming Yang, Tong-Ling Shan, Hao Zheng, Yan-Jun Zhou, Wu Tong, Fei Gao, Guang-Zhi Tong*, Hai Yu*. Protective efficacy of a high-growth reassortant H1N1 influenza virus vaccine against the European Avian-like H1N1 swine influenza virus in mice and pigs, veterinary microbiology, 2018, 222:75-84.(通讯作者)
(2)Ying-Feng Sun, Lei Zhou, Ting Bian, Xiang-Xue Tian, Wei-Ke Ren, Chao Lu, Li Zhang, Xiu-Li Li, Mao-Sheng Cui, Han-Chun Yang*, Hai Yu*. Efficacy evaluation of two commercial modified-live virus vaccines against a novel recombinant type 2 porcine reproductive and respiratory syndrome virus. Veterinary microbiology, 2018, 216:176-182.(通讯作者)
(3)Xiao-Qian Gong, Bao-Yang Ruan, Xiao-Min Liu, Peng Zhang, Xiu-Hui Wang, Qi Wang, Tong-Ling Shan, Wu Tong, Yan-Jun Zhou, Guo-Xin Li, Hao Zheng, Guang-Zhi Tong*, Hai Yu*. The PB2-K627E mutation attenuates human-origin H3N2 swine influenza virus in cultured cells and in mice. Research in veterinary science, 2018, 117:54-56(通讯作者)
(4)Xiao-Qian Gong, Ying-Feng Sun, Bao-Yang Ruan,Xiao-Min Liu, Qi Wang, Hai-Ming Yang, Shuai-Yong Wang, Peng Zhang, Xiu-Hui Wang, Tong-Ling Shan, Wu Tong, Yan-Jun Zhou, Guo-Xin Li, Hao Zheng, Guang-Zhi Tong*, Hai Yu*. PA-X protein decreases replication and pathogenicity of swine influenza virus in cultured cells and mouse models. Veterinary Microbiology.2017, 205:66-70.(通讯作者)
(5)Ying-Feng Sun, Xiu-Hui Wang, Xiu-Li Li, Li Zhang, Hai-Hua Li, Chao Lu, Chun-Lei Yang, Jing Feng, Wei Han, Wei-Ke Ren, Xiang-Xue Tian, Guang-Zhi Tong, Feng Wen, Ze-Jun Li, Xiao-Qian Gong, Xiao-Min Liu, Bao-Yang Ruan, Ming-Hua Yan*, Hai Yu*. Novel Triple-Reassortant H1N1 Swine Influenza Viruses in Pigs in Tianjin, Northern China. Veterinary Microbiology. 2016, 183:85-91.(通讯作者)
(6)Feng Wen, Jihong Ma, Hai Yu*, Furu Yang, Meng Huang, Yanjun Zhou, Zejun Li, Guangzhi Tong*. Protective efficacy of a high-growth reassortant swine H3N2 inactivated vaccine constructed by reverse genetic manipulation. Journal of veterinary science. 2014, 15(3):381-8. (通讯作者)
(7)Feng Wen, Hai Yu, Furu Yang, Meng Huang, Shen Yang, Yanjun Zhou, Zejun Li, Guangzhi Tong. Efficacy of a high-growth reassortant H1N1 influenza virus vaccine against the Classical swine H1N1 subtype influenza virus in mice and pigs. Archives of virology. 2014, 159(11):2957-67. (通讯作者)
(8)Hai Yu, Yanjun Zhou, Guoxin Li, Jihong Ma, Liping Yan, Bin Wang, Furu Yang, Meng Huang, Guangzhi Tong. Genetic diversity of H9N2 influenza viruses from pigs in China: a potential threat to human health? Veterinary Microbiology. 2011, 149:254-261.(第一作者)
(9)Hai Yu, Rong-Hong Hua, Qiang Zhang, Tian-Qiang Liu, Hui-Li Liu, Guo-Xin Li, Guang-Zhi Tong*. Genetic evolution of swine influenza A (H3N2) in China from 1970 to 2006. Journal of Clinical Microbiology. 2008, 46: 1067-1075.(第一作者)
(10)Hai Yu, Gui-Hong Zhang, Rong-Hong Hua, Qiang Zhang, Tian-Qiang Liu, Ming Liao, Guang-Zhi Tong*. Isolation and genetic analysis of human origin H1N1 and H3N2 influenza viruses from pigs in China. Biochem. Biophys. Res. Commun. 2007, 356: 91-96.(第一作者)

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